MIT Sloan finance professor Andrew Lo applies a hedge fund approach to increasing investment in drug development
Lo does not fault Big Pharma for this dilemma, noting that most large pharmaceutical companies are public companies entrusted with a fiduciary duty to generate returns for shareholders. Nor does he blame venture capitalists, as they are not in business to risk a $30 million investment in one company’s projects. It appeared that neither public nor private equity was the best vehicle to fund biomedical innovation.
The alternative is what Lo and his colleagues at MIT Sloan have devised, a $30 billion megafund to develop drugs treating cancer, and a smaller, less-than-$1 billion investment portfolio targeting orphan drugs. The large amount of the megafund is based on evidence that it requires at least $200 million in out-of-pocket costs to investigate and develop a single therapeutic compound, from beginning to end. For a high rate of success, the fund would need at least 150 of these shots.
The smaller portfolio for orphan diseases recognizes the significantly higher odds of a new orphan drug receiving FDA approval versus those aimed at curing cancer—22 percent versus 6 or 7 percent.
Both portfolio financing strategies are in the proposal stage, and Lo is confident of their eventual success. Until then, his campaign to apply financial tools to curing deadly illnesses continues. It’s worth a shot.
(The fund had $55 million)
"Now the world must show its colours," Merkel told the fifth informal meeting in Berlin of representatives of 35 countries, which was held to discuss a new climate change treaty.
"Every delay comes at a high cost," she said.
The 750 million euros form part of Germany‘s contribution to build up the green climate fund, which has been set up to help developing nations address climate change. Germany has spent 3.2 billion euros in recent years on efforts to tackle climate change.
"In Germany we are accepting our responsibility," the chancellor told the meeting, which is known as the Petersberg Climate Dialogue and which was created to overcome differences in the international community so that a new accord can be signed by the end of 2015.
The United Nations-sponsored green climate fund hopes to raise up to 100 billion dollars a year by 2020 to help with the promotion of climate-friendly businesses and to boost renewable energy.
By Kirk Kardashian Published Mar 25, 2014
Professor Andrew Bernard reframes the conversation on how to increase trade from developing nations.
1.2 Focus of this project This project reviews national government- funded outward mobility scholarship schemes in eleven countries (Brazil, China, Egypt, India, Indonesia, Kazakhstan, Mexico, Pakistan, Russia, Saudi Arabia and Vietnam) with the goal of better understanding why governments sponsor these programmes; how they are designed, administered, and funded; who participates and where they study; and what impact the programmes are having...
Estudio de @madridnetwork "Modelos de negocio en contenidos digitales" http://126.96.36.199/imgArticulos/Documentos/635315104927835991.pdf— Emilio Martínez (@aemiliusmg) April 2, 2014
David Meyer, April 1, 2014 Gigaom.com/2014/04/01/telefonica-buys-cloud-desktop-startup-eyeos/
“Were you expecting me to jump in?” he asked, a look of genuine surprise on his face.
Silence really can be golden. Here's my HBR blog on Knowing When to Shut Up, a vital cultural skill! http://t.co/bLbXLohy98— Erin Meyer (@ErinMeyerINSEAD) April 2, 2014
Erin Meyer is an affiliate professor of organizational behavior specializing in cross-cultural management at INSEAD in Fontainebleau, France, where she is the program director for two INSEAD executive education programs: Managing Global Virtual Teams and Management Skills for International Business.
She is the author of The Culture Map: Breaking Through the Invisible Boundaries of Global Business (PublicAffairs, due June 2014).
“I highly recommend this book to both the professional and leisure reader. Erin has shown to be one of the main representatives of the next generation scholars who combine deep conceptual models with very practical applications. A must-read!”—Fons Trompenaars, Author of Riding the Waves of Culture
4yfn.com/programme/25 (3 days)
Prince speaks from 1:00 min
Key Factors to Become a Global Startup, The Spanish Institute for Foreign Trade (ICEX) curates this panel on Internationalization. Four internationally successful Spanish entrepreneurs will be the participants. Some of them are living outside, and from there to grow their businesses in Spain. These entrepreneurs will explain the difficulties they found when setting up their businesses.
In February 2011, the president of the European Commission, José Manuel Barroso, appointed him as a principal adviser and head of the analysis team at the Bureau of European Policy Advisers, the president's personal think-tank.
Before that, Legrain was a visiting fellow at the European Institute of the London School of Economics, a senior fellow at the Lisbon Council for Economic Competitiveness and Social Renewal...
Shortlisted for the 2007 Financial Times/Goldman Sachs Business Book of the Year Award
"Mr. Legrain performs an invaluable service; he makes a good case for the unpopular cause of free flows of people. The book is a superb combination of direct reportage with detailed analysis of the evidence."--Martin Wolf, Financial Times
"Mr. Legrain has assembled powerful evidence to undermine the economic arguments against immigration."--Economist
"In all important respects Legrain is right on target…. In the context of the fearful chatter that surrounds the subject, sense as good as this needs cherishing."--Guardian
Hbr.org/2013/10/seven-reasons-why-africas-time-is-now, by Jonathan Berman
Andrew Delbanco, Director of American Studies at Columbia University ( www.columbia.edu/cu/amstudies ), is the author of College: What it Was, Is, and Should Be (Princeton University Press (March 20, 2012) (Finalist for the 2012 Book of the Year Award in Education).
The Center for American Studies offers students the opportunity to explore the experience and values of the people of the United States as embodied in their history, literature, politics, art, and other enduring forms of cultural expression.
Andrew Delbanco for his insight into the American character, past and present. He has been called “America’s best social critic” for his essays on current issues and higher education. As a professor in American studies, he reveals how classics by Melville and Emerson have shaped our history and contemporary life.
It is also true, however, that such training does not provide an adequate foundation for addressing the more abstract, but profoundly important, questions that ultimately must guide global policy and decision-making. For example:
In answering such questions, advances in science and technology (for example, new methods of energy production, surveillance, or online learning) will have a key role to play. But moral and ethical questions never yield fully to technical solutions; they also require an understanding of humanity’s social and cultural heritage. Science can help us to attain the life we want, but it cannot teach us what kind of life is worth wanting...
Jagdish Bhagwati speaks frankly in F&D magazine about international trade, US business lobbies&French culture http://t.co/fZdpZ5TAA9— IMF (@IMFNews) November 27, 2013
DeansTalk, 18 February 2012, Professor Jagdish Bhagwati, Columbia Business School, "Brain-Drain Panic Returns — This Time to Africa"
DeansTalk, 27 December 2011, "In Defense of Globalization", book
Bruce Corman Norbert Greenwald (Wikipedia) is a professor at Columbia University's Graduate School of Business31 Aug 2012. Columbia Business School professors Joseph Stiglitz and Bruce Greenwald discuss co-teaching the EMBA course Globalization, Markets, and the Changing Economic Landscape, while students share their experiences studying with such accomplished — and politically divergent — economic luminaries.
Youtube, 9 May 2013
Sanjay G. Reddy, Associate Professor of Economics at The New York School for Social Research, discusses inequality and globalisation, the ethics of economics and how to determine growth.
Professor Reddy refers to the use of other economic indicators other than GDP (as Porter) and to the report of Commission on the Measurement of Economic Performance and Social Progress (www.stiglitz-sen-fitoussi.fr)
The Institute has partnered with pre-eminent international institutions aligned to its mission with a view to expanding its global community, enhancing dialogue, leveraging networks and creating synergies. In Asia, the Institute’s partners currently include:
Its global partners currently include:
The Institute is also in discussion with the London School of Economics and Political Science with the intention of entering into agreements for specific collaboration and partnerships.
Johnson Graduate School of Management at Cornell University
Academic Council of Fung Global Institute
Open Doors, supported by a grant from the Bureau of Educational and Cultural Affairs at the U.S. Department of State, is a comprehensive information resource on international students and scholars studying or teaching at higher education institutions in the United States, and U.S. students studying abroad for academic credit at their home colleges or universities.
Data from the 2012 Open Doors Report was released on November 12.
Download the 2012 Open Doors Briefing Presentation (2 MB, PDF, 38 pages)
A growing population, increasing shortages of resources, and national economies that are heavily in debt – the world is facing enormous challenges over the coming decades. Business is going to play a key role in solving these problems. “Never before, have companies and society been so closely connected,” says Pierre Tapie, President of the ESSEC Business School.
Together with Keio Business School in Tokyo, the School of Management of Fudan University in Shanghai, ESSEC Business School in France and the Business School of the University of Mannheim, Tuck forged an alliance of leading business schools from all parts of the world. (CouncilOnBusinessAndSociety.com) The alliance has a clear goal: to debate central economic and societal questions of the future, and to develop problem-solving approaches, while embedding them in research and education. More than 200 high-profile professors, business representatives, and students from the home countries of the five alliance partners participated in the first Forum and the focus was on questions that are both current and controversial: How can we best shape corporate governance? How should business leaders deal with the increased scrutiny of corporate actions? And what solutions exist for the tension-laden issue of balancing profitability with responsibility to multiple stakeholders?
These are topics that will have an impact on the education of future managers as well. A study conducted amongst graduate students at the five cooperating business schools shows that future leaders in the United States already regard ethical conduct as one of the most important qualities of a successful top manager. Internationally, this attribute ranks second to competence in financial questions, but ahead of both strategic orientation and the ability to motivate employees...
Jean-Pierre Lehmann, Founding Director, Evian Group at IMD, Lausanne, Switzerland.
Sir, In the catalogue of bad ideas (of which there have been many recently), surely that of a European Union-Japan free trade agreement deserves a gold medal for sheer imbecility (“Brussels to push Japan for trade deal”, July 18)...
In the process, the multilateral trade regime has been dramatically eroded and the WTO negotiations have become an expensive farce – expensive in terms of time, money, environmental footprint (all those needless high-level trade meetings), carbon dioxide emissions (all the hot air generated) and in the costs to global trade governance...
Globalization’s jobs math, June 2012
Over the past three decades, a global labor market has taken shape, spurring a massive movement from “farm to factory” in emerging markets and boosting output and productivity. But today, the strains on this labor force are becoming painfully evident.
The McKinsey Global Institute’s latest report, The world at work: Jobs, pay, and skills for 3.5 billion people (available on mckinsey.com), finds that market forces will fail to resolve demand and supply imbalances for tens of millions of skilled and unskilled workers alike.
In an accompanying video interview, former deputy governor of the Reserve Bank of India Rakesh Mohan highlights some of the challenges facing policy makers and business leaders.d supply imbalances for tens of millions of skilled and unskilled workers alike. In an accompanying video interview, former deputy governor of the Reserve Bank of India Rakesh Mohan highlights some of the challenges facing policy makers and business leaders....
Based on current trends in population, education, and labor demand, the report projects that by 2020 the global economy could face the following hurdles:
Download PDF, 36 pages
The world is bumpy: globalization and new strategies for growth draws on three sources of original research: The 2011 Globalization Survey, an online survey of 992 global business executives conducted for Ernst & Young by the Economist Intelligence Unit; in-depth interviews with senior executives and high-level experts conducted at end- 2011; and data from Ernst & Young’s Globalization Index 2011, which measures the 60 largest countries by GDP according to their degree of globalization.
Jagdish Bhagwati is a Chazen Advisor, Professor of Economics and Law at Columbia University, and Senior Fellow in International Economics at the Council on Foreign Relations. He recently edited, with Gordon Hanson, Skilled Migration Today.
While developed countries are angst-ridden over mostly illegal immigration by unskilled workers from developing countries, a different set of concerns has surfaced in Africa, in particular, over the legal outflow of highly skilled people to developed countries. This outflow is supposedly a new and damaging “brain drain,” with rich countries actively luring away needed skills from poor countries.
This fear is misplaced...
First, stop crying over the fact that the diaspora is not returning home. Instead, nurture the loyalty of professionals settling abroad, so that they assist their home countries in a variety of ways...
...when development has taken off, and conditions have improved sufficiently to attract people back to their homelands, the hugely increased diaspora would indeed return, as they have done in India, South Korea, and China.
A collaboration between Harvard and MIT:
Press "Play" once inside Explore Interactive Visualizations
|"'Complexity' Predicts Nations' Future Growth,"
The Wall Street Journal, October 26, 2011
|"Is ‘complexity’ the key to economic growth?"
The Washington Post, October 26, 2011.
The Economist, October 27, 2011.
|"Harvard economist warns about world economy,"
ABC News (Australia), October 27,2011.
In Defense of Globalization is an important contribution to an often incoherent debate. As we expect from Mr.Bhagwati, it is cogently argued and well written. It sets out a persuasive case in favour of globalization. And because of Mr. Bhagwati’s impeccable credentials, there is a better chance his book will be given a fair hearing than might be the case with some other authors. Put simply, Mr. Bhagwati has “street cred.”
Anne Krueger, The Financial Times
Why globalisation works—and how to make it work better, The Economist, Apr 29th 2004
"An outstandingly effective book.... Until further notice In Defense of Globalization becomes the standard general-interest reference, the intelligent layman's handbook, on global economic integration."
...As you might expect, given the thrust of the author's previous academic and policy work, Mr Bhagwati regards liberal trade—the principal driver of globalisation—as essential to raising the incomes and improving the longer-term development prospects of the world's poor.
The Centre for Economic Policy Research, founded in 1983, is a network of over 750 researchers based mainly in universities throughout Europe, who collaborate through the Centre in research and its dissemination. The Centre's goal is to promote research excellence and policy relevance in European economics. CEPR Research Fellows and Affiliates are based in over 237 different institutions in 28 countries (90% in the EU). Because it draws on such a large network of researchers, CEPR is able to produce a wide range of research which not only addresses key European policy issues, but also reflects a broad spectrum of individual viewpoints and perspectives. CEPR has made key contributions to a wide range of European and global policy issues for over two decades.
How are technology leaders helping their organizations adapt to the accelerating change and complexity that mark today’s competitive and economic landscape? To find out, we spoke in person with 3,018 CIOs, spanning 71 countries and 18 industries. Public and private sector CIOs described both the challenges and opportunities from increasing complexity. They shared how they are innovating with technology for organizational success.
Executive summary PDF 2011 Global CIO Study -- The Essential CIO
Achieving Development Goals through Knowledge Sharing
Switzerland topped the global ranking, followed by Sweden, The Netherlands, the United States, Finland, Singapore, Norway, Canada, the UK, France, Australia, Japan, Malaysia, the Czech Republic, New Zealand, Israel, Slovenia, the Republic of Korea, and Thailand.
Titled "Networks for Prosperity: achieving development goals through knowledge sharing", the report was funded by the Spanish MDG Achievement Fund (MDG-F) (526 million euros so far) as part of a project that aims to establish a global knowledge system for private sector development. The report lays the basis for policy recommendations that will help developing countries acquire and adapt private sector development know-how.
Businessworld, 03 Dec 2011
The next 50 years will be defined by two important trends - both favouring India. The world's population is about 7 billion, of which 5 billion are poor. Companies typically target the 2 billion rich. Over the next 50 years, the projection is that we will have 12 billion people, of which 10 billion will be poor. So, the biggest opportunity for corporations is to convert the poor into a consuming base, so that they become an even bigger opportunity over the next 50 years.
However, you need innovation to serve the poor. I recently wrote a piece on a $300 house for the poor. Once you construct a home, it becomes a reservoir for other products. Apple, for instance, does not sell a single iPhone to the poor. If you could make an iPhone for $5, there is a $25-billion market. Even for a giant like Apple, that's a big revenue opportunity.
The second big trend is sustainability. This planet cannot be sustained if the 5-billion poor turn into consumers...
Wikipedia entry UNCTAD, United Nations Conference on Trade and Development
Report of the Secretary-General of UNCTAD to UNCTAD XIII - Development-led globalization: Towards sustainable and inclusive development paths
The key to inclusive development lies in the institutional and policy links which ensure that growth promotes social development, while social development supports economic growth. The Millennium Development Goals (MDGs) (UNDG) have added poverty, employment and social objectives to the international policy agenda, and have indicated the need for a significant scaling-up of resources to finance new investments in social infrastructure and safety nets, along with the formation of new partnerships to accelerate progress on human development. p48
Development with Impact: Innovation and Partnerships, Nov 03, 2011 | By Bill Gates
Development with Impact: Innovation and Partnerships from The Gates Notes
In a report presented to world leaders at the G20 summit in Cannes, France, Bill outlined recommendations to encourage innovation and new partnerships that increase the value and delivery of development aid. Read the report and download a copy (PDF)...
In a packed Leede Arena at the Tuck Investiture Ceremony, Immelt told the MBA candidates to think globally, have the courage to make difficult decisions, be problem solvers, connect with people, and understand context...
external focus, imagination and creativity, decisiveness, clear thinking
Globalization TrendLab 2011: "Global Risk: New Perspectives and Opportunities, (PDF, 42 pages)" April 7-8, 2011.
Page 37 and 38 have a list of the more than 30 scholars and policymakers from around the world who gathered in Philadelphia for a two-day conference.
The financial and economic crisis has heightened everyone’s awareness of systemic risk. Confidence in the ability of decision-makers, policymakers and institutions to handle such risks has been shattered. Psychology, a culture of destructive self-interest, and social processes have also been invoked as part of a complex set of conditions that led to the debacle. In turn, the crisis has accelerated some prevailing demographic, economic, and social trends, including population aging, political tensions, geopolitical instability and environmental degradation, as the focus of attention has unavoidably shifted towards short-term, immediate concerns. The crisis has placed the issue of systemic risk at the top of the global agenda, forcing analysts and policymakers to make a stark distinction between what is important and what is actually urgent.
In this white paper we provide an overview of the causes, consequences, and potential solutions to the problem of risk, focusing on economic and financial aspects, while also paying attention to political, social and environmental risks associated with the crisis and its aftermath. The analysis represents the outcome of a collective, multi-disciplinary effort at understanding risk by a group of more than 30 scholars and policymakers from around the world who gathered in Philadelphia for a two-day conference.
The analysis begins with the conventional explanations of the crisis, further adding political considerations, institutional constraints, psychology, and social processes. This prepares the stage for the assessment of the effectiveness of policy interventions during the crisis which, while averting a massive meltdown, generated a number of additional problems, both short-term and long-term. Failures in global governance and in understanding complex ripple effects are also explored. Risks building up in emerging economies—from financial to political and demographic—are presented as a stark reminder that global instability is punctuated by a growing number of troubled hot spots.
The conference participants identified four action items. First, global governance needs to be enhanced, a task that is not easy as a changing of the guard takes place due to the ascendancy of the emerging economies. Second, regulation must both set parameters for self-regulation and establish a set of cushions, bells and whistles to ameliorate the possibility of further systemic crises. Third, policymakers and scholars ought to adopt a more humble attitude in terms of the extent to which they are able to understand and overcome the complexities posed by crises. And fourth, as people adopt shorter time horizons due to incentives, demographics, politics, and cognitive biases, it is important to remain on the alert for the weaknesses and faults in the global economic, political, and social architecture.
Article of the Financial Times, by Della Bradshaw, July 21, 2011.
The Kellogg school at Northwestern University is to establish a network of hubs on three continents, says Sally Blount, who has been dean at the school for just a year. As well as Chicago, the school is expected to set up two more centres, one of which will be in Asia.
“To be a global player you have to have more than one home,” says Prof Blount...
Article of The New York Times, July 19, 2011.
ATHENS — An emergency meeting of European leaders in Brussels on Thursday to discuss another Greek bailout will decide the future of the euro. If they do what they have done so often since the crisis first began in Greece some 18 months ago, they will simply have kicked the can down the road. Contagion is almost inevitable. A problem that began in the periphery has now moved to the center, and while Spain and Italy have been the most shaken, other nations will almost surely be affected in coming months.
What needs to be done is by now well-known: Issue European bonds, using the collective borrowing power of the European Union, and pass the low interest rates onto the countries in need, combined with a growth strategy that will engender needed revenues...
INSEAD claims to be the quintessential global business school, yet it lacks a permanent home in the U.S. The school's new dean, Dipak Jain, offers his take on the global MBA.
How can any educational institution lay claim to being "the business school for the world" when it lacks a real presence in the U.S., the world's largest single economy?
Includes rankings by variables:
Business Environment - time/cost to start a business
Quality of research institutions
Knowledge - Creation, Impact, Diffusion
Talks about bschool cases, including that of Playboy´s entrance in Indonesia:
Soochow University will soon open a branch campus in Laos, becoming the first Chinese university to establish a campus abroad. How does this development fit into China’s national higher education strategy? What are the likely benefits of the campus for China and for Laos, and how does the initiative fit into current directions of international branch campus development?...
...Soochow University is part of China's 'Project 211', a reform plan to enhance the international position and prestige of Chinese higher education institutions in the world. This aim should be reached by improving institutional capacity of higher education, strengthening science and technology, and by improving the teaching and research infrastructure at selected Chinese universities...
Globalization is the hot topic in management education these days. In the past two years, elite business schools have initiated a slew of programs and partnerships designed to cultivate leaders who can work in cross-cultural environments with ease...
U.S. graduate business schools are losing their iron grip on the thriving market for international M.B.A. students.
At the 25 U.S. graduate-business programs that award the largest numbers of degrees to international students, applications for the 2011 fall semester declined 4%, according to a survey released Tuesday by the Council of Graduate Schools, based in Washington, D.C.
Although international applications to all American business schools rose by 4%, that figure paled in comparison to the 12% growth in international bids to U.S. programs offering degrees in engineering and physical and earth sciences, the survey said...
...This is the view of Paul Danos, dean of Tuck business school in the US.
In terms of curriculum, he says, there has been a massive convergence in recent years. “If you went to a business school in India, America, Europe or Japan you would find that they teach fundamentally the same topics,” he says. There’s no way that an American school would teach only American case studies, and when they are studying entrepreneurialism in Chinese schools they look at Silicon Valley. “Schools want to look at the gold standard, and they don’t care if that is American, Chinese or German.” The fierce market in business schools, plus the global marketplace for faculty, means that if Ghemawat’s ideas are adopted, they will quickly be adopted everywhere.
What you should look for in a good school, then, is not the curriculum, but the way that it is taught. And here, the old schools have a huge advantage – they are rich enough to teach well. Small-group and one-to-one teaching are expensive and “unless you have a ton of money behind you it is hard to set up that sort of school,” Danos says. American schools have been raising money for a hundred years – they run on endowments and fund-raising, they get a lot of money from alumni.
It would take decades for schools in India and China, say, to reach the same level. And even then, would it be worth “duplicating something that is already there” in America and Europe? Even if in twenty years time the American economy is no longer the world’s biggest, so what? “Look at how small Switzerland is, and at the power of Swiss banking,” says Danos. Just because India or China has a growing economy, it doesn’t follow that it is the best place in the world to go for your business education. In fact, we are more likely to see movement in the opposite direction. Newness has sparkle, but oldness has its attractions too. “Globalisation,” says Danos, “goes both ways.”
Julia Johnson, Financial Post Magazine · Tuesday, Mar. 1, 2011
Canadian business schools are responding to student demands for more international experience and learning opportunities. The benefits, however, stretch far beyond this country’s borders
Stephanie Hamilton knew she wanted to get international experience and make global business connections when she was looking for a school to pursue her MBA...
Robert Bruner is the dean of the Darden Graduate School of Business at the University of Virginia and co-author of the report, "Globalization of Management Education," AACSB International, 2011. (on BizDeansTalk, "The landmark 300-plus-page report is the most thorough examination of the globalization of management education ever" - Poets & Quants)
New research has revealed a sizable gap between what the business world needs and what business schools provide to their students. What's standing in the way and what can business schools do to step up their game?
We should do better.
What's standing in the way? The need for capital to transform the schools, the talented faculty to implement the transformation. Nationalist or localist cultures. Regulatory barriers to the mobility of institutions, faculty, and students across borders. Restrictions on the freedom of speech and association. Even a lack of sheer imagination.
Given such barriers, one can easily envision a widening variance among schools. Some schools are surmounting the barriers one way or another. The vast majority will not. Much like the widening gap in income between the "haves" and "have nots" in many countries, it is easy to envision a widening competence gap in regard to globalization.
We should worry about this because it should be the mission of business schools to spread the light of global best practices and competencies. The widening gap is antithetical to creating the kind of world in which we enjoy gains from trade, rising standards of living, and even the diplomatic benefits that accrue from strong trading relationships. Even if you don't believe in the internationalist view of joint benefits, education about globalization matters because of the competitive standing of one's country. The recent finger-wagging of my CEO friend probably knows no borders.
Schools should help each other. First, we should hold the bar of excellence high, and perhaps raise it a few notches when it comes to globalization. There is no more powerful force in academia than peer pressure. Schools should share their best practices and capabilities. Finally, we should offer a robust voice to our constituencies -- and especially governments -- to gain the resources needed to produce globally competent and confident graduates.